17. Februar 2022

Investigating the Waste in our Cells: So That We Can Soon Forget About Alzheimer’s

Vienna (Austria), February 17th, 2022 – A ‚waste collection‘ tidies up our cells. If something does not go according to plan, serious diseases such as Alzheimer’s or Parkinson’s may develop. Molecular biologist Sascha Martens from the University of Vienna together with international partners – researchers of the University of Pennsylvania, Monash University, the Max Planck Institute of Biophysics in Frankfurt and the UC Berkeley – investigate the associated process: autophagy. Martens and his team have recently published new results on these mechanisms in Nature Communications and The Journal of Biological Chemistry.


(In English only)


Recent publications:

The Journal of biological chemistry: https://pubmed.ncbi.nlm.nih.gov/35007534/

In this publication the team has shown how the initial seeds for the membrane that will engulf the waste are brought to it.


Nature Communications: https://pubmed.ncbi.nlm.nih.gov/34471133/

In this publication the team discovered how several molecules work together to accumulate the waste in larger particles, such that it can be efficiently wrapped up and disposed of by the autophagy machinery.


More info here: